An SC injection
- The medicine is injected under the skin, into fatty tissue, but not any deeper into the muscle
- Before injecting on your own, or with the help of a caregiver, your doctor or nurse will train you on how to properly inject ACTEMRA. You or your caregiver should inject for the first time, with the help of a healthcare professional, during this training session
- The total injection time will be about 35 minutes: 30 minutes to allow the syringe to warm up to room temperature, and then 5 minutes to prepare for the injection, give the injection, and properly dispose of the syringe
An intravenous, or IV, infusion given in a rheumatologist’s office or in an infusion center
- During an IV infusion, liquid medicine is given by needle directly into your vein
- At the infusion, you’ll sit in a comfortable chair or lie down on a cot or bed
- An infusion lasts about 1 hour. So you may want to bring entertainment like music, a book, or games
This is important to know because ACTEMRA gives you and your rheumatologist the flexibility to find the treatment method that works best for your rheumatoid arthritis (RA).
Whichever method you choose, ACTEMRA has been proven to help relieve a range of RA symptoms, including swollen and tender joints, and to ease activities like walking.
- Shortness of breath or trouble breathing
- Skin rash
- Swelling of the lips, tongue, or face
- Chest pain
- Feeling dizzy or faint
- Moderate or severe abdominal pain or vomiting
For patients starting on 1 prefilled syringe every 2 weeks, you and your rheumatologist may decide to change your dose to 1 prefilled syringe every week if you aren’t getting the results you need. Your doctor may choose to increase, lower, or hold your dose based on other factors, including changes in your blood tests.
Patients less than 220 lb (100 kg)
1 prefilled syringe every 2 weeks
Patients 220 lb (100 kg) or more
1 prefilled syringe once a week
ACTEMRA IV infusions
When you begin taking ACTEMRA, the recommended starting dose is 4 mg/kg, and could be increased by your doctor to 8 mg/kg, based on your response to treatment. While on ACTEMRA, your rheumatologist will closely monitor your lab test results to see how you’re responding to treatment.
There is no set time for a dose adjustment, so keep track of how you’re feeling after each infusion. If you feel like you’re not getting the level of symptom relief you want, you should talk to your rheumatologist so he or she can decide if an increase in your dose is appropriate. Depending on your blood tests, it’s also possible your rheumatologist may decrease, increase, or hold your dose. ACTEMRA is not for everyone.
While rare, multiple sclerosis has been diagnosed in some people taking ACTEMRA.
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Please click expand button below to see Important Safety Information for ACTEMRA.