How ACTEMRA Is Taken
ACTEMRA for RA is FDA approved and available as:

An SC injection

  • The medicine is injected under the skin, into fatty tissue, but not any deeper into the muscle
  • Before injecting on your own, or with the help of a caregiver, your doctor or nurse will train you on how to properly inject ACTEMRA. You or your caregiver should inject for the first time, with the help of a healthcare professional, during this training session
  • The total injection time will be about 35 minutes: 30 minutes to allow the syringe to warm up to room temperature, and then 5 minutes to prepare for the injection, give the injection, and properly dispose of the syringe

An intravenous, or IV, infusion given in a rheumatologist’s office or in an infusion center

  • During an IV infusion, liquid medicine is given by needle directly into your vein
  • At the infusion, you’ll sit in a comfortable chair or lie down on a cot or bed
  • An infusion lasts about 1 hour. So you may want to bring entertainment like music, a book, or games

This is important to know because ACTEMRA gives you and your rheumatologist the flexibility to find the treatment method that works best for your rheumatoid arthritis (RA).

Whichever method you choose, ACTEMRA has been proven to help relieve a range of RA symptoms, including swollen and tender joints, and to ease activities like walking.

It’s important to keep in mind that ACTEMRA may lead to allergic reactions, including death. These events may happen with any IV infusion or injection treatment, even if they have not happened before.

Signs include:

  • Shortness of breath or trouble breathing
  • Skin rash
  • Swelling of the lips, tongue, or face
  • Chest pain
  • Feeling dizzy or faint
  • Moderate or severe abdominal pain or vomiting
Understanding Your Dose
ACTEMRA SC injections

For patients starting on 1 prefilled syringe every 2 weeks, you and your rheumatologist may decide to change your dose to 1 prefilled syringe every week if you aren’t getting the results you need. Your doctor may choose to increase, lower, or hold your dose based on other factors, including changes in your blood tests.

Patients less than 220 lb (100 kg)
1 prefilled syringe every 2 weeks

Patients 220 lb (100 kg) or more
1 prefilled syringe once a week

ACTEMRA IV infusions

When you begin taking ACTEMRA, the recommended starting dose is 4 mg/kg, and could be increased by your doctor to 8 mg/kg, based on your response to treatment. While on ACTEMRA, your rheumatologist will closely monitor your lab test results to see how you’re responding to treatment.

There is no set time for a dose adjustment, so keep track of how you’re feeling after each infusion. If you feel like you’re not getting the level of symptom relief you want, you should talk to your rheumatologist so he or she can decide if an increase in your dose is appropriate. Depending on your blood tests, it’s also possible your rheumatologist may decrease, increase, or hold your dose. ACTEMRA is not for everyone.

While rare, multiple sclerosis has been diagnosed in some people taking ACTEMRA.

"I enjoy the flexibility injecting ACTEMRA gives me, because I am so busy."
treating her RA with ACTEMRA SC injections
"When I get my infusion once a month, the nurses keep an eye on things to make sure I'm not having any infusion reactions. They are so careful and thorough with me, and that puts me at ease."
treating her RA with ACTEMRA IV infusions

Individual results may vary. Genentech sponsors advocates and compensates them for their time and expense in presenting their stories.

ACTEMRA & You Patient Support

Join our patient support program, ACTEMRA & You, to get 24/7 access to tools and resources to help you manage life with RA.

Please click expand button below to see Important Safety Information for ACTEMRA.

Before reading more, please see the Important Safety Information for ACTEMRA.
During an IV infusion, liquid medicine is given by needle directly into your vein.